Creative BioMart's strong expertise in protein structure enables us to accelerate your project by providing protein structure prediction and assessment services, including structural modeling and structural assessment. This service can help us accurately understand the 3D structural information of proteins and the interactions between proteins and proteins (or other molecules), which are very important for research in biology, medicine and pharmacy.

The function of a protein is determined by its structure, and many methods have been developed for the study of protein structure. It has traditionally been difficult to determine the 3D structure of proteins by X-ray crystallography, spectroscopic techniques, atomic force microscopy and electron diffraction techniques. With the development of DNA sequencing technology, the gap between the number of proteins for which a large number of known sequences have been deduced from DNA and the number of proteins whose structures have been determined (such as the data in the protein structure database PDB) is increasing. In order to make up for this deficiency, theoretical prediction research has been gradually developed, and significant results have been achieved in predicting and evaluating protein structures through computational molecular biology.

Fig 1. Three approaches of protein structure prediction. (Chen J, et al., 2020)

Creative BioMart can provide the most affordable protein structure prediction and assessment services with the fastest turnaround time to meet your downstream needs. Our protein structure prediction flowchart is as follows:

Creative BioMart provides the following protein structure prediction and assessment services for your scientific research:

• Protein Structure Modeling Service

Protein structure modeling is the calculation of the natural spatial structure of protein molecules from the amino acid sequence of the protein. Traditionally, methods such as homology modeling, fold identification and de novo simulations are the preferred options. Creative BioMart can provide you with a variety of protein structure modeling services.

• Protein Structure Assessment Service

Selecting the appropriate performance evaluation index of protein structure prediction algorithm is an important issue that directly affects the measurement and comparison of the pros and cons of various protein structure prediction algorithms. Creative BioMart provides a wide range of protein structure evaluation services through experimental and algorithmic evaluation of predicted protein structures.

If you have any special requirements about our protein structure prediction and assessment services, please feel free to contact us. We are looking forward to working together with your attractive projects.

Reference

1. Chen J, Siu S W I. (2020) Machine learning approaches for quality assessment of protein structures[J]. Biomolecules. 10(4): 626.

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