Solutions for Nanobiotechnology
Solutions

Solutions for Nanobiotechnology

Nanobiotechnology has multiple potentials to advance medical science and thereby improve healthcare practices around the world, especially novel nanoparticles and nanodevices, which have a huge positive impact on human health. Based on our extensive experience in protein engineering, researchers can use protein engineering strategies to design novel nanobiomaterials, nanobiodevices, and nanobiosystems, which are expected to open up new fields of nanobio/bio-nanotechnology. Creative BioMart is commmitted to developing nanoscale materials combined with various engineered proteins for therapeutics, diagnostics, biosensing, bioanalysis and biocatalysis. We have the ability to provide global customers with the best solutions for novel protein-based nanobiomaterials.

Background

Bionanotechnology refers to the use of engineered biomolecules to form nanoscale materials. These biomolecules include DNA, lipids, peptides and proteins. The study found that organized quaternary assemblies of proteins as nanofibers and nanotubes are serving as bioscaffolds for many applications, including tissue engineering, drug delivery, biomimetic nano, and biosensor development. The field of protein engineering has always played a central role in biological sciences, biomedical research and biotechnology. Protein engineering also designs useful and valuable building blocks for nanobio/bio-nanotechnology to fabricate various nanoparticles, nanowires, nanofibers and nanotubes with nanoscale structures. The 20 natural amino acids have unique chemical properties that enable complex interactions, making proteins particularly attractive for nanobiosensor development. Furthermore, protein nanotubes are of particular interest in biomedical applications, where they enable detection of disease-related analytes and desired reactions in vivo.

A summary of nanobiomaterials and their applications. 
Fig 1. A summary of nanobiomaterials and their applications. (Nagamune T, 2017)

Custom Solutions for Nanobiotechnology

Solutions for Nanobiotechnology

Protein-based structures are rich in diversity and can be used in the fields of bio-nanotechnology and nanomedicine. The application of protein engineering in the field of nanobiotechnology has been shown to be beneficial for sustainable development. Creative BioMart is dedicated to using state-of-the-art protein engineering strategies to produce nanoparticles, nanowires, nanofibers and nanotubes with modified dimensions and desired chemical properties, enabling many clinical applications of nanobiotechnology such as disease diagnosis, targeted drug delivery and molecular imaging. Our researchers are very interested in discovering new and increasingly valuable solutions to design novel nanobiomaterials to help you be more successful.

In particular, two protein engineering strategies, rational design and directed evolution have been successfully used to design and fabricate novel nanobiomaterials with highly ordered size and complexity. We offer the following solutions for protein-based nanobiomaterials:

Protein-based nanoparticles have many useful properties that make them highly attractive as biological nanomaterials. We have successfully established platforms of protein-based nanoparticles for drug delivery, nanomaterial synthesis, vaccines and biocatalysis.

Protein-based nanotubes have well-defined structures, are assembled under physiologically relevant conditions, and are easily manipulated by protein engineering approaches. We have successfully immobilized peptides and proteins on carbon nanotubes for molecular imaging biosensors, microelectronics, fuel cells, and wires for drug delivery systems.

Fiber materials, especially nanofibers, are increasingly used in biomedical research due to their high surface area-to-volume ratio, mechanical strength, porosity, and tunability. We have successfully synthesized a variety of natural proteins and synthetic peptides into nanofibrous materials, which are widely used in tissue engineering, drug delivery, wound healing and biosensors.

Our Capabilities

  •  Providing tailored solutions for the application of protein engineering in nanobiotechnology. Creating nanobiomaterials with highly ordered size and complexity to transform future disease diagnosis, treatment and prevention.
  •  Use of rational protein design and directed evolution for site-specific modification of proteins with diverse natural and non-natural functions to synthesize nanobiomaterials.
  •  Applying expertise and creativity to solve problems, provide complete, professional interpretation of data, understand experimental results, and better integrate external research and internal data.
  •  A unique fusion of biotechnology and nanotechnology that can truly integrate classic microtechnology into molecular biology methods.

Creative BioMart has created successful high-quality diverse protein-based nanobiomaterials, providing powerful solutions for drug delivery, vaccines, and biocatalysis. We have professionals who listen carefully to your needs and can provide you with comprehensive support before, during and after your experiment. Each project will be individually designed to meet the needs of our customers and described in a detailed project report. Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our solutions, please contact us without hesitation.

Reference

  1. Nagamune T. (2017) Biomolecular engineering for nanobio/bionanotechnology[J]. Nano convergence. 4(1): 1-56.
For research use only, not intended for any clinical use.