Solutions for Biomaterials
Solutions

Solutions for Biomaterials

Today, engineered proteins with enhanced biological functions/other properties and the ability to form hydrogels or other forms of biomaterials are becoming increasingly important, which play a vital role in reconstructive surgery, tissue engineering and regenerative medicine effect. Based on our extensive experience in protein engineering, researchers can use protein engineering strategies and the possibility of engineering protein/protein domain combinations to create novel protein biomaterials for the biomedical field. Creative BioMart is committed to developing a variety of protein biomaterials for controlled drug delivery, gene therapy or tissue engineering. We have the ability to provide global customers with the best solutions for new smart biomaterials.

Background

With the constant influx of new concepts and advancements, biomaterials have been developed for human well-being since time immemorial. The primary goal of first-generation biomaterial design is to maintain a balance between mechanical and physical properties with minimal toxicity to host tissues. Biomaterials play a very important role in biomedicine and tissue engineering, directly affecting cell activity and microenvironment. A variety of techniques are used to create a vast array of natural, artificial, and recombinant polymers, biomaterials that are widely used in tissue regeneration, drug delivery, etc. But advanced, next-generation biomaterials are still lacking. The advent of protein engineering has opened up new avenues for the design of biomaterials integrated with the human body. Protein-based biomaterials have emerged as an attractive alternative due to their inherent properties, such as cell-cell interactions, structural support, and cellular communication. These protein-based biomaterials have enormous capabilities and aim to expand their application in human healthcare.

Overview of biomaterial strategies for protein presentation. 
Fig 1. Overview of biomaterial strategies for protein presentation. (Dorogin J, et al., 2021)

Custom Solutions for Biomaterials

Solutions for Biomaterials

Compared to other fields of protein engineering, biomaterial design presents unique challenges because mechanical behavior plays a crucial role in determining the success or failure of material applications. Creative BioMart is dedicated to developing a variety of state-of-the-art protein engineering strategies to generate protein biomaterials known for their biodegradability, biocompatibility and biofunctionality from combinations of natural, synthetic or engineered proteins and protein domains. Our researchers are very interested in discovering new and increasingly valuable solutions for designing novel smart biomaterials to help you be more successful.

Emerging interest in designing biomaterials that better integrate and respond to damaged tissues is expected to open many doors for improved patient treatment strategies. We offer the following solutions for protein-based biomaterial applications:

Wound healing materials have important applications in the field of biomedicine. We develop a variety of protein-based wound healing materials with specific properties by utilizing rationally designed protein engineering strategies to meet the healing needs of different types of wounds.

Biological or tissue adhesives have a variety of potential medical applications. We develop a variety of protein-based adhesive biomaterials for enhanced bleeding control and wound healing by utilizing rationally designed protein engineering strategies.

Biomaterials can provide physical support for engineered tissues to guide cells. We have developed a variety of protein-based biomaterials for tissue regeneration by utilizing rationally designed protein engineering strategies to create an attractive alternative to synthetic polymer scaffolds or harvested natural scaffolds.

Our Capabilities

  • Providing tailor-made solutions for the application of protein engineering in biomaterials. The challenge of creating well-defined multifunctional materials to guide cellular and tissue behavior.
  • Designing proteins by rational design or directed evolution, primarily considering their biological function and mechanical properties, to create desirable variant libraries.
  • Applying expertise and creativity to solve problems, provide complete, professional interpretation of data, understand experimental results, and better integrate external research and internal data.
  • Not only using protein biomaterials as scaffolds for tissue engineering, but also exploring synthetic polymers as well as various functional/structural peptide domains and natural/engineered proteins as basic biomaterials for suitable biomedical applications.

Creative BioMart has created successful high-quality multiple protein-based biomaterials, providing powerful solutions for applications in biomedicine and tissue engineering. We have professionals who listen carefully to your needs and can provide you with comprehensive support before, during and after your experiment. Each project will be individually designed to meet the needs of our customers and described in a detailed project report. Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our solutions, please contact us without hesitation.

References

  1. Brindha J, Balamurali M M, Chanda K. (2019) Evolutionary approaches in protein engineering towards biomaterial construction[J]. RSC advances. 9(60): 34720-34734.
  2. Dorogin J, Townsend J M, Hettiaratchi M H. (2021) Biomaterials for protein delivery for complex tissue healing responses[J]. Biomaterials Science. 9(7): 2339-2361.
For research use only, not intended for any clinical use.