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Enzymes used in the environment generally transform foreign organisms and many pollutants. In order to adapt to the development of the environment, it is necessary to improve the stability and effectiveness of these enzymes. The application of enzymes and protein engineering in the environment is an important field. Based on our extensive experience in protein engineering, researchers can range from experimental protein construction and theoretical protein design to environment applications of engineered proteins. Creative BioMart is committed to developing a variety of environmental enzymes with broad substrate specificity, stability, high selectivity and efficacy, etc. We have the ability to provide global customers with the best solutions for protein engineering applications in environment.
The quality of life on earth is closely related to the overall quality of the environment. As people become more environmentally conscious, people have begun to search more deeply for alternative technologies for clean energy. The two major technologies currently used to deal with pollution include biotechnological treatment of waste and bioremediation of polluted environments, both of which convert pollutants into non-toxic products through microorganisms. However, microbial transformation requires the expression of enzymes with sufficient catalytic activity. In addition, many synthetic compounds that cannot be degraded by microorganisms persist in the environment as pollutants. Consequently, there is a growing interest in enzymatically catalyzed transformation of synthetic compounds. With the development of protein engineering, it has become possible to construct specific enzyme mutants based on predicting the modifications required for certain specific aspects of enzyme performance. Scientists have successfully designed enzymes that play a role in the detoxification of exogenous compounds, and improved these environmental enzyme properties through protein engineering, including catalytic performance, resistance to reactive compounds and products, enzyme stability and substrates scope.
Fig 1. Methods to remediate and degrade microplastics in marine environment. (Bansal M, et al., 2021)
Protein engineering offers the possibility to implement enzymes for biodegradation and bioremediation by increasing their degradation capacity or conversion rate or by directly manipulating their structure to endow them with new desirable properties. Creative BioMart is committed to developing a variety of state-of-the-art protein engineering technologies to improve key properties such as substrate specificity, affinity, pH, temperature dependence and stability over time for environmental enzymes, thereby enhancing the quality of the environment. Our researchers are very interested in discovering new and increasingly valuable solutions to various environmental protein engineering related problems to help you be more successful. We provide the following solutions in environment:
Oxygenases are one of the key enzymes that play a central role in the degradation/detoxification of compounds. Based on our understanding of structure-function relationships, our protein engineers are paving the way for the use of oxygenases in chemical synthesis and bioremediation by using protein engineering approaches.
Laccases are multicopper oxidoreductases considered by many in the biotechonology field as the ultimate “green catalysts”. Our protein engineers use rational and random mutagenesis to build flexible and comprehensive biocatalysts.
Peroxidase assists in the removal of environmentally relevant harmful pollutants. Our protein engineers have directed evolution of various native proteins to increase peroxidase activity and/or alter substrate specificity.
Haloalkane dehalogenase is an important enzyme for the bioremediation of toxic environmental pollutants and the removal of pollution. Our protein engineers have successfully used computational rational protein engineering and design methods to improve the thermal stability of haloalkane dehalogenases.
By improving the properties of enzymes through protein engineering, our solutions help maintain a clean environment with the following advantages:
Creative BioMart has created successful high-quality enzymes for the environment solutions for our customers. We have professionals who listen carefully to your needs and can provide you with comprehensive support before, during and after your experiment. Each project will be individually designed to meet the needs of our customers and described in a detailed project report. Our customers have direct access to our experts and give timely feedback to any online inquiries. If you are interested in our solutions, please contact us without hesitation.
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