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Creative BioMart is an award-winning biotechnology company that provides the most comprehensive protein engineering-related service portfolio for the biotechnology industry, from library construction to antibody engineering, including large-scale expression and crystallization.
Our protein engineering platform is based on gene recombination technology, combined with the research of protein chemistry, protein crystallography and protein dynamics, to design and modify the genes encoding proteins purposefully.
It is our responsibility to meet your protein design needs efficiently and accurately. Customized services can provide professional solutions for customers in multiple fields.
Directed evolution is an effective means to improve protein function and activity, mainly in the laboratory to simulate natural evolution of protein engineering methods. The steps are mainly repeated gene mutation, selection and amplification. Creative BioMart provides a variety of services based on protein directed evolution strategies to accelerate your project, including the construction and screening of mutation libraries, gene amplification, successful protein engineering from utilizing directed evolution, etc.
Rational design refers to the design based on the comprehensive structural and functional information of the target protein. The use of computer modeling for sequence-based protein design and structure-based protein design has been rapidly developed. Creative BioMart provides a variety of services based on protein rational design strategies to accelerate your project, including protein structure prediction and evaluation, knowledge-based secondary structure self-assembly design, computational design of therapeutic proteins, in-silico pharmacology, etc.
An important area of protein engineering research is the identification of those post-translationally modified proteins and their modification sites, and the determination of the modified functions and the interactions of the modified proteins in cellular functional networks. Creative BioMart provides a variety of protein post-translational modifications to increase the functional diversity of the proteome, including phosphorylation, glycosylation, nitrosation, methylation, sulfonation, acetylation, hydroxylation, carbonylation and ubiquitination modification, etc.
Synthesis of target proteins according to different properties is of great significance for the exploration and application of proteins in biotechnology and medicine. Starting with gene synthesis and codon optimization, Creative BioMart uses various protein expression systems, purification techniques, and renaturation techniques to solve practical problems encountered in protein synthesis. Based on our experienced team, we ensure that we can synthesize proteins close to the natural structure.
